Among heavy
drinkers, reducing alcohol consumption has a potent antihypertensive effect that may
be just as important as pharmacotherapy, a US trial (link) has found.
Blood pressure
reductions of 12mmHg systolic and 8mmHg diastolic were seen in hypertensive
patients taking part in a trial of alcohol dependence interventiuons,
researchers report in the journal Addiction (103: 1622-28) this month.
The study of
almost 1400 alcohol-dependent patients being treated with naltrexone or
acamprosate found that the reductions in BP were seen in the first few weeks of
starting treatment and were sustained among those who maintained abstinence or
reduced alcohol consumption during the 16 week trial.
The
antihypertensive effect was seen in both men and women and among people of all
ages.
“If maintained in
the long term, such reductions would be expected to result in improved survival,”
the study authors say.
They note that it
is already known that consuming more than two drinks a day is associated with
higher BP, and they say their results suggest that hypertensive patients be
screened for heavy drinking.
“For alcohol
dependent people, treatment for alcoholism should be considered a major
component of anti-hypertensive therapy,” they conclude.
Interesting. Are the numbers you quote averages for the whole group (or top of a range)? If averages some of the group studied after stopping alcohol would have much larger reductions.
Posted by martin knapp 2/10/2008 8:30:48 AM
I have anecdotally noticed this effect with several pts I advised to stop drinking prior to considering antihypertensives. The BP improved earlier than any actual wt loss that may follow.
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Posted by martin knapp 2/10/2008 8:30:48 AM
Posted by Judith Ellis 2/10/2008 11:18:41 PM
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