Watch those drug holidays for fracture risk

Experts urge caution with temporarily ceasing bisphosphonate therapy

Drug holidays for patients with osteoporosis are riskier than previously thought and need further assessment, a team of US endocrinologists argue.

Temporarily ceasing bisphosphonate therapy is often recommended to lower the risk of rare adverse events, such as medication-related osteonecrosis of the jaw and atypical femur fracture.